Synthetic portion of fermented molecules
Deuterated Molecules
Peptides in Solid, Solution Phase & Hybrid technology
Cyanation, Hydrogenation, Bromination, Cryogenic
Carbohydrate Chemistry
Steroidal Bile Acids & Vitamin D Derivatives
Organometallic Carbon-carbon bond formation
Heterocyclic Compounds
Synthetic Portion of Fermented Molecules
Our expertise lies in synthesizing and modifying molecules derived from fermentation processes, thus advancing the development of pharmaceuticals and chemicals. We work towards maintaining the stereo genic centre during the chemical conversions on a large scale and attaining the desired conversion with minimal impurity generation.
Capabilities:
Deuterated Molecules
Neuland Labs has developed expertise in deuteration technology to streamline the process of developing and scaling deuterated compounds. Our team is well-versed in the design and development of synthetic routes for deuterated APIs while maintaining isotopic purity, thereby offering improved metabolic stability, reduced toxicity, and enhanced efficacy.
Capabilities:
Peptides in Solid, Solution Phase & Hybrid technology
Neuland Labs excels in peptide synthesis, offering expertise in solid-phase, solution-phase, and hybrid approaches, crucial for peptide-based drug development. Additionally, Neuland has the capability to manufacture these products at a large scale, including pseudoprolines, isoacyl peptides, Dmb-derivatives, N-methyl amino acids, etc.
Capabilities:
Cyanation, Hydrogenation, Bromination, Cryogenic
Our team at Neuland brings extensive experience and expertise in conducting catalytic hydrogenation reactions, both homogenous and heterogenous, in inert environments to ensure the success of specific hydrogenation processes. We are equipped to undertake enantioselective reduction reactions utilizing Rh catalysts.
Capabilities:
Carbohydrate Chemistry
This specific branch of organic chemistry could be challenging due to several complicating factors, including polarity, chemical complexity, the absence of a chromophore and the need to use complex and custom protection strategies for targeted carbohydrates. Neuland Laboratory has considerable experience in the area of synthesis of complex carbohydrates and their related derivatives.
Capabilities:
Steroidal Bile Acids & Vitamin D Derivatives
Neuland Labs has a strong focus on synthesizing steroidal bile acids such as Ursodeoxycholic acid (used to treat liver disorders) and Vitamin D derivatives like Calcitriol, critical components in pharmaceutical and medicinal chemistry.
Capabilities:
Organometallic Carbon-Carbon Bond Formation
Neuland Laboratory excels in the formation of organometallic carbon-carbon bonds, a key technique in the synthesis of complex organic molecules.
For example, Suzuki-Miyaura cross-coupling reactions are used to create aryl-aryl bonds in molecules like Valsartan.
Capabilities:
Synthetic lab & manufacturing facilities are equipped with specific reactors to handle air-sensitive reaction for metal-catalysed cross-couplings, such as Sonogashira, Suzuki, Heck, Buchwald, and Chan-Lam reactions, at scales ranging from 5 to 50 kg.
Heterocyclic Compounds
Neuland laboratory is proficient in the synthesis and modification of heterocyclic compounds, fundamental in pharmaceutical research. We offer the most comprehensive selection of heterocyclic building blocks that can be used in a broad range of synthetic protocols, including lithiation and palladium catalysed cross coupling.
Capabilities:
A dedicated facility with a capacity of 5-100 kg for producing customized solutions for heterocyclic compounds at commercial scale.
Chiral Compounds Manufacturing
Controlling chirality of enantiomers is a crucial aspect during manufacturing process. At Neuland, we specialize in developing and scaling up a diverse array of chiral synthesis methods for our customers. This ensures establishment of the optimal route while maintaining high quality and efficiency.
Capabilities: